Microscopy with microfluidics in microgravity using FlightScope

Authors: Thomas Wareing, Alexander Stokes, Katrina E. Crompton, Koren Murphy, Jack Dawson, Yusuf Furkan Ugurluoglu, Connor Richardson, Hongquan Li, Manu Prakash & Adam J. M. Wollman

Link: https://www.nature.com/articles/s41526-025-00470-3

Abstract: With planned missions to the moon and Mars, it has never been more important to study the impact of microgravity on biological organisms. Parabolic flights are one of the most accessible microgravity research platforms but present challenges: short periods of microgravity and aircraft vibration. Live-imaging is necessary to readout any real-time phenotypes so we developed FlightScope, a new microscopy and microfluidics platform to study dynamic cellular processes in microgravity.

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